Cellular and Molecular Immunology is a great book. It contains far more detail on basic matters than Immunobiology; indeed, so rich is the material that the authors suggest that readers may want to skip certain sections, which they have set against a gray background. Unlike Immunobiology, this book cites references to specific points, which the reference list supplements with review articles. Throughout, the results of experiments, usually in mice, form the backbone of the presentation. Indeed, the appendix is a summary of techniques in cellular and molecular immunology. The coverage of some topics is exceptionally detailed, but there are surprising lapses, such as the single page on somatic mutation of immunoglobulin V genes, the brief discussion of the repertoire of these genes (which misstates the number of human heavy-chain V genes), and the out-of-date section on lymphokines.